3-D Polymer Coating (P)

The NEXTERION® 3-D Polymer coating is the ideal surface for the covalent immobilization of biomolecules containing primary amines (NH2 groups) such as proteins, antibodies and most peptides. Furthermore, for amino-modified biomolecules like glycans or oligonucleotides this surface may be the coating of choice.

SCHOTT specifically developed the 3-D Polymer coating as a dedicated substrate surface for printing low-density antibody microarrays. It produces excellent signal-to-background ratios, and exceptionally wide dynamic ranges compared to conventional “two-dimensional” coatings through a unique combination of low non-specific binding characteristics, and high probe loading capacity.

Produced in ISO class 5 clean room conditions using a proprietary thin-film deposition process and running a stringent quality control system, the 3-D Polymer coating is offered in standard as well as in custom formats.
  • Coating Chemistry
HP
Three-dimensional, hydrophilic polymer coating activated with N-Hydroxysuccinimide (NHS) esters.
  • Shelf Life
    Twelve months for sealed packages when stored at –20°C.
 
  • Immobilisation Method
    Covalent binding via amine reactive chemistry.
 
  • Probe Types
    • Amino-linked glucans
    • Antibodies and antibody fragments
    • Functional proteins such as enzymes or receptors
    • Small protein fragments such as peptides
    • Amino-modified oligonucleotides 16 to 70 mers
Exhibitions & Events
12.
December
Exhibition International MicroNano Conference 2017, Amsterdam, Netherlands, 12-12 to 12-13-2017
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