The NEXTERION® AL coating represents a uniform surface featuring aldehyde groups, that are readily reactive to primary amines in order to bind all types of amino-containing or amino-modified bio-molecules.
The covalent bond formed at the terminus of the nucleic acid offers both: stability and maximal base pairing opportunity. The covalent binding diminishes sample loss during the course of experiments and permits stringent washing steps, which reduce background noise and allow greater sensitivity. Additional immobilization steps, such as baking or UV cross-linking, are not required for immobilization.
Produced in ISO class 5 clean room conditions using a standardized process and running a stringent quality control system, aldehydesilane coated substrates are available in standard as well as in custom formats.