SCHOTT Vitryxx® Bioactive Glass 

Product Description

Bioactive Glass Powder for Cosmetics and Cosmeceutical Products

Chemically, bioactive glass is an amorphous structure (like all glasses) that consists solely of elements found in the body - silicon, calcium, sodium, phosphorous and oxygen. Decades of research and studies have demonstrated that bioactive glasses are highly biocompatible. For cosmetics and cosmeceutical products, the unique biocompatibility of bioactive glasses translates to absolute skin compatibility, as has been demonstrated repeatedly in several long- and short-term human skin patch tests.

When activated with water, bioactive glass releases the ions of its composition as they possess a high bioavailability. These form a mineral matrix on the particle surface equivalent to that of natural hydroxy apatite.

Due to the mineral and inorganic character of SCHOTT Vitryxx® bioactive glass, this class of anti-aging ingredient is insensitive to light and temperature extremes.


In recent years, bioactive glass has been discovered to exhibit the following properties within cosmeceutical products:

1. Reduces redness on the skin
In cosmeceutical products, tests have shown, e.g., reduction of redness induced by UV treatment or chemical skin barrier damage.

2. Reduces visibility of wrinkles
Fast optical in-vivo topometry of human skin shows a significant reduction in visibility of wrinkle length and depth within a short period of time when using bioactive glass within cosmeceutical products.

3. Anti-oxidant
As a new class of anti-aging ingredients, Bioactive Glass in the form of finely grained powder shows clear anti-oxidative effects in in-vitro protein-carbonyl-assay and other test settings.

4. Mineral enrichment
The mineral enrichment effect of bioactive glass is triggered by small amounts of water. This leads to the release of minerals, mainly calcium and silica, which can bind to nails.


SCHOTT Vitryxx® is an excellent anti-aging ingredient for cosmeceutical products (such as skincare and post-procedure care) as well as microdermabrasion purposes.

As of today, a broad range of cosmeceutical products have been successfully formulated with SCHOTT Vitryxx®. These include:
  • Color Cosmetics (e.g. Mascara, Foundation, Eye Shadow, Lipsticks, Pressed Powder Blush)
  • Skin Care (e.g. Facial Cream, Skin Gel), Hair Care (e.g. Conditioner, Styling Gel)
  • Nail Care (e.g. Nail Enamel, Base Coat)
  • Men’s Care (e.g. Shave Cream, After Shave Balm)
  • Deodorants (e.g. Stick, Spray)
  • Bath/Cleaning (e.g. Bar Soap, Liquid Soap)

Technical Details

SCHOTT Vitryxx® Bioactive Glass Technology

In an aqueous environment a rapid ion exchange between the sodium ion of the bioactive glass matrix and the hydrogen ion from the water takes place. This exchange generally leads to an increase in the pH of the surrounding solution, which can be substantial for finely grained bioactive glass powders having high surface to volume ratios.

The fast release of sodium ions is accompanied by a somewhat slower release of other species like calcium ions, silica and phosphorous. These releases are caused by a very slow dissolution of the glass surface. Under certain conditions in solution, these species will precipitate onto the glass surface and other nearby surfaces, to form calcium and phosphorous containing layers. These surface layers can transform into crystalline hydroxycarbonate apatite (HCA) – the chemical and structural equivalent of bone material. The ability of bioactive glass to build such a surface is the reason for the bonding ability to human tissue and can be seen as a measure of the “bioactivity” of the glass.

Features / Specifications

SCHOTT Vitryxx® Bioactive Glass is a fine white powder that is odorless and tasteless. Due to its hydrophilic properties it must be stored dry.

Grain Sizes:
SCHOTT offers Vitryxx® Bioactive Glass in the following standard grain size. Customized grain sizes are also available upon request.

SM4.0 specified by d50: (4.0 ± 1.0) μm d95: ≤ 20 μm

Microbiological Properties:
Maximum content of microorganisms:

Total viable count ≤ 100 cfu/g
Yeasts and molds ≤ 100 cfu/g

Forms of Supply and Product Packaging

Vitryxx® is currently available in two forms.


  • Material number: MD01
  • Classification: Glass
  • Form of delivery: Powder, grain sizes upon request
  • INCI-name: Calcium Sodium Phosphosilicate
  • CAS 65997-17-3
  • EINECS 266046-0
  • Mass % 100 % (Vitryxx®)
Vitryxx® Bioactive Glass is suitable for waxy, solid, powder and highly viscous formulations.

Vitryxx®M Bioactive Glass/Mica
  • Material number: G018-270
  • Classification: Glass/Mica
  • Form of delivery: Powder, grain sizes upon request
  • INCI-name: Calcium Sodium Phosphosilicate/Mica
  • CAS 65997-17-3 (Vitryxx®)
  • CAS 12001-26-2 (Mica)
  • EINECS 266046-0 (Vitryxx®)
  • EINECS 310-127-6 (Mica)
  • Mass % 97-99% (Vitryxx®)
  • Mass % 1-9 % (Mica)
Vitryxx®M Bioactive Glass with Mica:
Pre-blending of SCHOTT Vitryxx® with Mica improves its dispersibility and enhances the appearance of the formulation. It is ideal for formulations like emulsions, liquids and low-viscous formulations.


For more information, please refer to our quality assurance processes or the product information.


Exhibitions & Events
Exhibition LED Japan, Tokyo, Japan, 01-29 to 01-31-2020
Exhibition SPIE PhotonicsWest, San Francisco, USA, 02-04 to 02-06-2020
Electronic Packaging
SCHOTT North America, Inc.

15 Wells Street
Southbridge, MA 01550
E-Mail to SCHOTT+1 (508) 765-7450
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