The NEXTERION® 3-D Hydrogel coating provides the ideal surface for the covalent immobilization of biomolecules containing primary amines (NH2 groups) such as proteins, antibodies and most peptides. Additionally, for amino-modified biomolecules like glycans or oligonucleotides this surface may be the coating of choice.
This type of coating has proven to be a very attractive alternative to the commonly used nitrocellulose-coated slides, especially when low background noise or slide transparency are important. It ensures an extremely low non-specific binding and helps preserving the native three-dimensional structure of complex bio-molecules, thus maintaining conformation and functionality. As a result, it attains excellent signal-to-background ratios.
Produced in ISO class 5 clean room conditions using a proprietary thin-film deposition process and running a stringent quality control system, the 3-D hydrogel coating is offered in standard and custom formats.