03-25-2019, Mainz, Germany / New York City, NY, U.S.
World’s first lubricant-free prefillable glass syringe launched at DCAT 2019
Lubricants have long been a necessary evil for prefillable syringes. They aid in reducing the injection force to make the treatment more comfortable for the patient, yet could also influence and harm the drug. Pharma packaging specialist SCHOTT has successfully tackled this challenge and presents syriQ BioPure® lubricant-free – the first prefillable glass syringe (PFS) that completely eliminates the need for silicone or similar substances. The new syringe will be available in the course of 2019.
To meet the needs of the growing market for biologics that are ultra-sensitive to silicone, which applies to an estimated 10 to 15 percent of the pipeline, syriQ BioPure® lubricant-free refrains from siliconization of the syringe barrel. To still maintain a consistent gliding force, great emphasis was laid on an accurate geometry. The new syringes are made of FIOLAX® glass tubing that is 100 % inspected with the help of a big data process named perfeXion®, ensuring tight dimensions and a high cosmetic quality of each barrel. Silicone-free plungers and stoppers from leading component suppliers round out the concept and eliminate the risk of lubricants interacting with sensitive biologics. In addition, syriQ BioPure® lubricant-free also features ultra-low tungsten residuals as well as low adhesive residuals in the needle stake to limit the risk of Extractables & Leachables (E&L).
Pharma packaging specialist SCHOTT presents syriQ BioPure® lubricant-free – the first prefillable glass syringe (PFS) that completely eliminates the need for silicone or similar substances. Picture: SCHOTT
“Quite often, pharmaceutical manufacturers opt to use vials instead of pre-filled syringes to avoid silicon contamination”, says Nicolas Eon, Global Product Manager at SCHOTT. “With syriQ BioPure® lubricant-free, we allow a new class of drugs to be manufactured and stored in PFS – a packaging class that offers a great way to save time for both patients and clinicians and reduce healthcare costs.”
SCHOTT is a leading international technology group in the areas of specialty glass and glass-ceramics. The company has more than 130 years of outstanding development, materials and technology expertise and offers a broad portfolio of high-quality products and intelligent solutions. SCHOTT is an innovative enabler for many industries, including the home appliance, pharma, electronics, optics, life sciences, automotive and aviation industries. SCHOTT strives to play an important part of everyone’s life and is committed to innovation and sustainable success. With more than 15,500 employees at production sites and sales offices in 34 countries, the group has a global presence. In the 2017/2018 fiscal year, SCHOTT generated sales of around $2.5 billion.
Gregory FCA on behalf of SCHOTT